KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFN
All Species:
49.7
Human Site:
Y127
Identified Species:
91.11
UniProt:
P31947
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P31947
NP_006133.1
248
27774
Y127
Y
L
K
M
K
G
D
Y
Y
R
Y
L
A
E
V
Chimpanzee
Pan troglodytes
XP_528202
382
42115
Y262
Y
L
K
M
K
G
D
Y
Y
R
Y
L
A
E
V
Rhesus Macaque
Macaca mulatta
XP_001110323
248
27784
Y127
Y
L
K
M
K
G
D
Y
Y
R
Y
L
A
E
V
Dog
Lupus familis
XP_544477
248
27815
Y127
Y
L
K
M
K
G
D
Y
Y
R
Y
L
A
E
V
Cat
Felis silvestris
Mouse
Mus musculus
O70456
248
27695
Y127
Y
L
K
M
K
G
D
Y
Y
R
Y
L
A
E
V
Rat
Rattus norvegicus
P63102
245
27753
Y125
Y
L
K
M
K
G
D
Y
Y
R
Y
L
A
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511520
248
27538
Y127
Y
L
K
M
K
G
D
Y
Y
R
Y
L
A
E
V
Chicken
Gallus gallus
Q5ZMD1
245
27764
Y125
Y
L
K
M
K
G
D
Y
F
R
Y
L
A
E
V
Frog
Xenopus laevis
Q5XHK2
244
27740
Y125
Y
L
K
M
K
G
D
Y
Y
R
Y
L
S
E
V
Zebra Danio
Brachydanio rerio
Q7T356
242
27374
D124
F
Y
L
K
M
K
G
D
Y
Y
R
Y
L
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29310
248
28209
Y128
Y
L
K
M
K
G
D
Y
Y
R
Y
L
A
E
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20655
248
28049
Y127
Y
L
K
M
K
G
D
Y
Y
R
Y
L
A
E
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q01525
259
29143
Y131
Y
L
K
M
K
G
D
Y
H
R
Y
L
A
E
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.7
99.5
97.9
N.A.
96.3
69.7
N.A.
90.7
68.5
66.5
68.9
N.A.
64.9
N.A.
64.5
N.A.
Protein Similarity:
100
54.4
100
98.7
N.A.
97.9
83
N.A.
93.9
84.6
81.4
82.6
N.A.
79.8
N.A.
79.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
93.3
6.6
N.A.
100
N.A.
100
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
13.3
N.A.
100
N.A.
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
58.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
72.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
86.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
85
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
93
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
93
8
% E
% Phe:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
93
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
93
8
93
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
93
8
0
0
0
0
0
0
0
0
93
8
0
0
% L
% Met:
0
0
0
93
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
93
8
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
85
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
93
8
0
0
0
0
0
93
85
8
93
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _